The Ingredients: Trifluridine
Dosage Form and Administration: Solution/drops; Ophthalmic
Drug Trade Name: Viroptic
Firm: Monarch Pharms
Strength: 1%
New Drug Application Type: N
The Drug Application Number: 18299
Medicine Product Number: 1
Approval Date: 1/1/1982
Reference Listed Drug: Yes
Type: RX
Applicant Full Name: Monarch Pharmaceuticals Inc
Local Number: 35574

12-Step Facilitation Therapy

Twelve-step facilitation therapy is an active engagement strategy designed to increase the likelihood of a substance abuser choosing to become actively involved in 12-step self help groups and promote abstinence. One aspect of facilitation therapy is acceptance: realizing that drug addiction is a chronic illness over which one has no control; that life is unmanageable because of drugs, that willpower alone is insufficient to overcome the problem and that abstinence is the only alternative. Another aspect of facilitation therapy is surrender, which involves giving oneself over to a higher power, accepting the fellowship and support structure of other recovering addicted individuals and following the recovery activities laid out by the 12-step program. The final ingredient in a facilitation therapy is active involvement in 12-step meetings and related activities. While studies support the efficacy of 12-step programs in treating alcohol dependence, the research pertaining to other drugs a person abuses is more preliminary but promising for helping drug abusers sustain recovery.

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Laser Acne Treatment

Laser surgery has been in use for some time and reduces the scars left behind by acne, but doctors have done little research on lasers treatments for the prevention of acne. Doctors use the laser to address the following: to burn away the follicle sac from which hair grows; to burn away the sebaceous gland that produces oil; to induce oxygen in the bacteria, thereby killing them. Since lasers and intense pulsed light sources cause thermal damage to the skin, there are concerns that laser or intense pulsed light treatments for acne will induce hyperpigmented macules (spots) or cause long-term dryness of the skin. In the United States, the FDA has approved several companies, such as Candela Corp., to use a cosmetic lasers for the treatment of acne. However, efficacy studies have used very small sample sizes (fewer than 100 subjects) for periods of six months or less, and have shown contradictory results. Because laser treatment are relatively new, protocols remain subject to experimentation and revision, and treatment can be quite expensive. In addition, the company that produces some Smoothbeam laser devices recalled their products due to coolant failure, which had resulted in painful burn injuries to patients.