The Ingredients: Somatropin Recombinant
Dosage Form and Administration: Injectable; Injection
Drug Trade Name: Tev-tropin
Firm: Ferring
Strength: 5MG/VIAL
New Drug Application Type: N
The Drug Application Number: 19774
Medicine Product Number: 2
Approval Date: 1/4/2002
Reference Listed Drug: Yes
Type: RX
Applicant Full Name: Ferring Pharmaceuticals Inc
Local Number: 33497

Buprenorphine

Buprenorphine is a partial agonist of opioid receptors that carries a low risk of overdose. Buprenorphine reduces or eliminates withdrawal symptoms associated with opioid dependence but does not produce the euphoria and sedation caused by heroin or other opioids. In 2000, Congress passed the Drug Addiction Treatment Act, allowing qualified physicians to prescribe Schedule III, IV and V medications for the treatment of opioid addiction. This bill created a major paradigm shift that allowed access to opioid treatment in general medical settings, such as primary care offices, rather than limiting it to specialized treatment clinics. Buprenorphine was the first medication approved under the Drug Addiction Treatment Act and is available in two formulations: Subutex®, which is a pure form of buprenorphine and the more commonly prescribed Suboxone®, which is a combination of buprenorphine and the opioid antagonist naloxone. Suboxone is a unique formulation with naloxone that causes severe withdrawal symptoms when addicted individuals inject it to get high. Physicians who provide buprenorphine treatment for detoxification and or maintenance treatment in office must have special accreditation. The government requires these physicians to have the capacity to provide counseling to patients when indicated or to refer patients to those who do. Treatment of opioid addiction in an office can be cost-effective approach that increases the reach of treatment and the options available to patients. Many patients have life circumstances that make treatment in the office of a physician a better option for than specialty clinics. For example, a recovering addict may live far away from a treatment center or have working hours incompatible with the clinic hours. Addiction treatment is available in the office of a primary care physician, psychiatrist and other specialists, such as internists and pediatricians. Patients stabilized on adequate, sustained dosages of methadone or buprenorphine can function normally. Recovering addicts can hold jobs, avoid the crime and violence of the street culture and reduce exposure to HIV by stopping or decreasing injection drug use and other risky sexual behavior. Patients stabilized on medications can also engage more readily in counseling and other behavioral interventions essential to recovery and rehabilitation.

Skin Conditions

Here is a glossy of terms for skin conditions. Atrophic means thin. Wrinkled and blistered skin is fluid-filled. Bumps and crust or scabs indicate the formation of dried blood, pus or other skin fluid over a break in the skin. A cyst is a deep lesion that contains pus. Excoriation is a hollowed-out or linear area covered by a crust. Hives or wheals entail a pink swelling of the skin. Lichenification describes skin that has thickened. A macule is a smaller version of a patch or a flat discolored spot. A nodule or papule is a solid, raised bump. Raised bumps describe bumps that stick out above the skin surface whereas a patch is flat, and discolored. A pustule refers to a pimple, which is an inflamed lesion that looks like a pink bump. Scales are dead skin cells that appear as flakes or dry skin. A scar is fibrous tissue that has formed after a skin injury.